The number in China Pharmacopoeia: WS1-XG-031-2000

Snake Venom Source: Gloydius ussuriensi & Deinagkistrodon acutus.

Product description:

The active ingredient of Defibrase is a serine protease which is available in a pure single compound purified from the snake venom of Gloydius ussuriensi & Deinagkistrodon acutus. in China. The efficacy is similar to that of Tobishi’s (Japan) Batroxobin which is from the snake venom of Bothrops moojeni in Brazil. Defibrase from Gloydius ussuriensi & Deinagkistrodon acutus has a molecular weight of around 36KD, it cleaves Arg-Gly bonds in fibrinogen alpha chains, does not cleave fibrinogen beta chains. Defibrase has the property of dissolving thrombus, preventing thrombosis and improving microcirculation

Main therapeutic applications:

- Acute cerebral infarction.
- Myocardial infarction.
- Sudden deafness.
- Lung infarction.