Trimeresurus stejnegeri

040 L-amino-acid oxidase precursor (LAAO) (LAO) (TSV-LAO)

No.040
LOCUS    Q6WP39
DEFINITION L-amino-acid oxidase precursor (LAAO) (LAO) (TSV-LAO).
SOURCE Viridovipera stejnegeri (Stejneger's pit viper)
COMMENT
[FUNCTION] Catalyzes an oxidative deamination of predominantly hydrophobic and aromatic L-amino acids. Inhibits platelet aggregation. Has an ability to induce apoptosis, and hemorrhage. Has an antibacterial activity (By similarity). Has cytotoxic activity. Displays dose-dependent inhibition on HIV-1 infection and replication.
[CATALYTIC ACTIVITY] An L-amino acid + H(2)O + O(2) = a 2-oxo acid + NH(3) + H(2)O(2).
[COFACTOR] FAD (By similarity).
[SUBUNIT] Homodimer.
[SUBCELLULAR LOCATION] Secreted protein (By similarity).
[TISSUE SPECIFICITY] Expressed by the venom gland.
[PTM] Glycosylated.
[SIMILARITY] Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
FEATURES EC_number="1.4.3.2"
ORIGIN
001 mnvffmfsll flaalgscad drnpleecfr etdyeeflei arnglkatsn pkhvvivgag
061 msglsaayvl agaghevtvl easeraggrv rtyrndeegw yanlgpmrlp ekhrivreyi
121 rkfnlqlnef sqendnawhf vknirktvge vkkdpgvlky pvkpseegks aeqlyeeslr
181 kvekelkrtn csyilnkydt ystkeylike gnlspgavdm igdlmnedag yyvsfiesmk
241 hddifayekr fdeivdgmdk lptsmyraie ekvhfnaqvi kiqknaeevt vtyhtpekdt
301 sfvtadyviv cttsraarri kfepplplkk ahalrsvhyr sgtkifltct kkfredegih
361 ggksttdlps rfiyypnhnf tsgvgviiay gigddanffq aldlkdcgdi vindlslihq
421 lpreeiqtfc ypsmiqkwsl dkyamggitt ftpyqfqhfs ealtshvdri yfageytaha
481 hgwidssiks gltaardvnr asenpsgihl snddel
LENGTH 516 aa
MOLECULAR WEIGHT 58601 Da

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